University of Wisconsin–Madison

Journal Article Mini-Proposal in Biomolecular Chemistry 504

Professor Angela Kita, Biomolecular chemistry 

Purpose: As part of our end of the semester mini-symposium, you and a partner will prepare a 10 minute presentation about a paper of your choosing. In preparation, you will compose a mini-proposal about the paper you intend to select. We will review these proposals to ensure that the papers that are presented to the group are sufficiently broad and scientifically rigorous.

Pick an article from a well-respected, peer-reviewed journal (examples: Cell Press, PLoS, PNAS, Journal of Biological Chemistry, Science, Nature, etc.) on a topic that interests you. The article should 1) use a biochemical technique and 2) use some sort of model system (yeast, cell culture, animals, etc.) to answer an interesting biological question. There are literally 1000s of options that would be acceptable, so pick something that is interesting to you.

• Post your selected paper to the Canvas discussion board by 5pm on Tuesday 2/6.

• Insert text and figures into this document and submit it via Canvas before 5pm on Tuesday 2/20.

• Presentation draft (as a powerpoint) due on Canvas by 5pm Tuesday 4/24.

1. What is the citation of your paper? Use a journal-style citation that includes authors, title, journal, year, volume and page numbers (see citations in appendix D).

2. Using 3 sentences or less: Briefly describe the topic of study and the question you think this paper is attempting to address.

3. Using 4 sentences or less: Briefly describe what techniques the author use to address this question, and what the overall conclusion of the paper is. Do not simply restate the abstract, this should be in your words.

4. Pick one figure where the authors used a biochemical technique. Create a screen shot or download the image of this figure to paste into this document. In 4 sentences or less, describe the main point of this figure and how it fits into the overall story of the paper.

5. Pick one figure where the authors used an in vivo model. Create a screen shot or download the image of this figure to paste into this document. In 4 sentences or less, describe the main point of this figure and how it fits into the overall story of the paper.

6. In 4 sentences or less, describe what future directions or unanswered questions either the authors bring up in the discussion or that you thought of after reading the paper. How might these questions be addressed?

7. In 2 sentences or less, describe why you think this paper would have broad interest for your fellow students.